The mentioned findings are the most frequent indication for performing esophageal biopsy. Other studies reported that the mean number of esophageal eosinophils could be as high as 100-150 eosinophils/HPF this study, EoE diagnosis was based on signs of dysphagia and bolus obstruction (not possible to swallow and swallow not possible), eosinophilia on biopsy and special histologic findings. In these cases, the most common esophageal eosinophil presence is 25-35% as in our study. The grading system of esophageal eosinophilia recommends the following: eosinophils \> 5 % for disease without significant symptoms, \> 15 % for esophageal dysfunction (abnormal acid exposure, esophageal dysfunction, esophageal spasm, distal esophageal stricture or hiatal hernia), and \> 30 % for intractable symptoms or life-threatening esophageal dysfunction eosinophilia occurs mostly in the group of chronic inflammatory and allergic diseases like EoE and allergic bronchial asthma.
Imaging and biopsy are considered as the most reliable methods for the diagnosis of diseases The diagnosis of esophageal eosinophilia depends on the grade of eosinophilia and presence of symptoms. The diagnosis of esophageal eosinophilia in many cases is difficult due to the nonspecific signs and symptoms. The most valuable clinical information can be obtained from medical observation and physical tests, such as history, clinical examination, laboratory, imaging and endoscopy tests, especially in order to establish the stage of the disease and take the necessary steps for the correct medical prescription. treatment, patient’s mobility, food intake and clinical condition, an effort has been made to highlight the importance of the complementary use of these parameters to predict the likely individual survival and/or prognosis. Governments have developed monitoring and evaluation systems. EUROPEANS FOR EUROPEAN ECONOMIC COUNCILS (EEECs).